Metoclopramide hydrochloride

SKU: orb1309870

Description

Metoclopramide hydrochloride is a dopamine D2 receptor antagonist employed as an antiemetic agent. It is widely used in research to investigate gastrointestinal motility and vomiting mechanisms, with applications in both in vitro receptor binding assays and in vivo animal models of emesis.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	7232-21-5
MW	336.26
Purity	99.94% (May vary between batches)
Formula	C₁₄H₂₂ClN₃O₂·HCl
SMILES	Cl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
Target	AChR,5-HT Receptor,Dopamine Receptor
Solubility	DMSO:50 mg/mL (148.69 mM);H2O:61 mg/mL (181.41 mM);Ethanol:62 mg/mL (184.38 mM)

Bioactivity

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Target IC50	D2 receptor:483 nM (IC50)\|5-HT3 receptor:308 nM (IC50)

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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DopamineReceptor, Dopamine Receptor, Dopamine, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT, 5-HT Receptor, 5HT Receptor, gastro-oesophageal, gastroparesis, Maxolon, Inhibitor, inhibit, nausea, Metoclopramide, Metoclopramide HCl, Metoclopramide hydrochloride, Metoclopramide Hydrochloride, mAChR, vomiting, reflux, Serotonin Receptor

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Compound Identifiers

PubChem CID

23659 ↗

Key Properties

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No computed properties available.

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