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SRI-011381

SKU: orb1302989

Description

SRI-011381 is a novel small molecule agonist of the TGF-β signaling pathway. It is used in Alzheimer's disease research, showing potential to modulate neuroinflammation and promote neuroprotection in both cellular and animal models of neurodegeneration.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1629138-41-5
MW329.48
Purity99.11% (May vary between batches)
FormulaC20H31N3O
SMILESO=C(NC1CCCCC1)N(CC1CCNCC1)Cc1ccccc1
TargetTGF-beta/Smad
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.07 mM);DMSO:125 mg/mL (379.39 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TGFb, TGF-b/Smad, TGF-β/Smad, TGFβ, TGF-β, TGF-beta/Smad, TGFbeta, TGF-beta, TGFbeta/Smad, sclerosis, Smad, SRI011381, SRI-011381, SRI 011381, Transforming growth factor beta, α-SMA, collagen-1, inhibit, multiple, neuroprotective, NALP3, Inhibitor

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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SRI-011381 (orb1302989)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 90.00
5 mg
$ 110.00
10 mg
$ 160.00
25 mg
$ 280.00
50 mg
$ 430.00
100 mg
$ 630.00
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