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15-LOX-1 inhibitor 1

SKU: orb1693977

Description

9c(i472) is a potent 15-lipoxygenase-1 (15-LO-1) inhibitor (IC50 = 0.19 µM) that suppresses LPS/IFN-γ-induced NF-κB activity, iNOS expression, and lipid peroxidation in macrophage models. This compound is a valuable research tool for studying inflammation, oxidative stress, and related pathways in cellular assays.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2349374-37-2
MW412.87
FormulaC22H21ClN2O4
SMILESCCOC(=O)c1[nH]c2cc(Cl)ccc2c1\C=C\C(=O)NCc1ccccc1OC
TargetOthers,Lipoxygenase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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15-LOX-1 inhibitor 1 (orb1693977)

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